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Terms of Use

NATPARA.com (the "website") is owned and operated by Shire Human Genetic Therapies Inc., 300 Shire Way, Lexington, MA 02421 (“Shire Human Genetic Therapies”).

Shire Human Genetic Therapies welcomes its customers, alliance partners, suppliers, investors, employees, the scientific community, as well as the general public. The site is available to you for your information, interest and education about hypoparathyroidism.

The following terms of use, as may be amended from time to time in the sole discretion of Shire Human Genetic Therapies, including the Privacy Notice ("Terms and Conditions"), apply to any and all access to the website and your use of the website or its contents. By using this website you unconditionally accept and agree to be bound by these Terms and Conditions without qualification, limitation or other restriction. Your continued access and use of the website after any changes or amendments to the Terms and Conditions will constitute your acceptance of any such changes or amendments.

The website is designed to provide information about NATPARA to a wide variety of audiences. The information contained on the website is not intended to provide medical advice. NATPARA is available only by prescription. Healthcare providers should consult the Full Prescribing Information for instruction on the appropriate use of NATPARA. Hypoparathyroidism is a serious medical condition which cannot be diagnosed or treated based on the general information contained here. Patients should consult their physician to determine whether NATPARA is appropriate.

Patients are urged to consult with their treating physicians or other qualified healthcare professional before using any product, service or technique discussed in this website.

All information and materials posted on the website are provided "as is" with all faults. Such materials and information may contain errors, omissions or typographical errors or may be out of date. Shire Human Genetic Therapies makes no representation or warranty as to the accuracy or completeness of the information posted on or referenced on the website, including, without limitation, information prepared by third parties that is posted on the website or on websites that are linked to the website. Access to and use of all information, as authorized herein, is at the user's own risk.

Shire Human Genetic Therapies will use reasonable efforts to post materials on the website that are current as of the date posted. Shire expressly disclaims any duty to update such information. You acknowledge that Shire has not posted. Shire Human Genetic Therapies expressly disclaims any duty to update such information. You acknowledge that Shire Human Genetic Therapies has not reviewed and does not endorse the content of third party sites linked to and from the website and is not responsible for the content or actions of these other sites. Such third party sites are governed by the privacy policies and terms of use of their respective owners or operators. Your linking through the website to any third party site is at your own risk.

Any communication, information, materials or other content transmitted to Shire Human Genetic Therapies via the website is not confidential. For any content that you submit through the website, you grant Shire Human Genetic Therapies a worldwide, perpetual, irrevocable, royalty-free, non-exclusive, transferable, unrestricted right and license to use, reproduce, modify, delete in its entirety, adapt, display, transmit, publish, translate, create derivative works from, sell, sublicense, distribute, incorporate into other works, and otherwise exploit such content, in whole or in part, alone or with other materials, in any form, medium or technology now known or hereafter created or devised, throughout the world, for any purpose whatsoever, including without limitation informational, commercial and promotional activities, without compensation to you. Personal information submitted to the website will be used in accordance with the Privacy Notice.

The website is expressly owned and operated by Shire Human Genetic Therapies. Unless otherwise noted, the design, features and content on the website are owned by Shire Human Genetic Therapies or are licensed from third parties by Shire Human Genetic Therapies. You may view and use the website and its content only for your personal information. Except as set forth in these Terms and Conditions, Shire Human Genetic Therapies does not grant to you any right to use, reproduce, copy, modify, transfer, display, publish, sell, license, create derivative works, or distribute by any means, method or process the website or any of its content. You agree to use the website and its content only for lawful purposes.

It is the policy of Shire Human Genetic Therapies to enforce its intellectual property rights to the fullest extent permitted under law. All product names, regardless of whether or not they appear in large print or with the trademark symbol, are trademarks of Shire Human Genetic Therapies or its licensors or collaborators, unless otherwise noted. The content of the website, including any images or text, is copyrighted and may not be distributed, downloaded, modified, reused, reposted or otherwise used, except as provided herein, without the express written permission of Shire Human Genetic Therapies. The use or misuse of these trademarks, copyrights, or other materials, except as permitted herein, is expressly prohibited and may be in violation of copyright law, trademark law, communications regulations and statutes, and other laws, statutes and/or regulations.

In accordance with the Digital Millennium Copyright Act of 1998 (the "DMCA") and other applicable law, if you are a copyright owner and you believe that any content present on this website infringes a copyright you own, you or your agent may send Shire Human Genetic Therapies written notice pursuant to the DMCA requesting that Shire Human Genetic Therapies remove the content or restrict access to it. If you are a user who believes that your content that was removed, or to which access was disabled, is not infringing, or that you are permitted pursuant to applicable law or have the permission of the copyright owner or his, her, or its agent to exploit your content, you may send Shire Human Genetic Therapies a counter-notice. Please visit http://copyright.gov for further information if you wish to send a notice or counter-notice to Shire Human Genetic Therapies using the address below. Shire Human Genetic Therapies may allow users to submit content, including personal stories and other materials, to the website, subject to the restrictions set forth in these Terms and Conditions. By submitting any content to Shire Human Genetic Therapies or the website, you represent and warrant that:

  • you are the sole author of the intellectual property rights thereto, or a licensee with appropriate rights to allow Shire Human Genetic Therapies to use such content as set forth in these Terms and Conditions;
  • all "moral rights" that you may have in such content have been voluntarily waived by you;
  • you are at least 18 years old;
  • use of the content you supply does not violate these Terms and Conditions and will not cause injury to or violate the rights of any person or entity.

You further agree and warrant that you shall not submit any content that:

  1. concerns a use for which a product is not intended;
  2. is false, inaccurate or misleading, or that involves impersonating or misrepresenting any person or entity, or falsely stating or otherwise representing your affiliation with a person or entity;
  3. infringes or violates any third party's copyright, patent, trademark, trade secret or other proprietary rights or rights of publicity or privacy;
  4. violates any law, statute, ordinance or regulation or any obligation of confidentiality or other contractual obligation;
  5. is, or may reasonably be considered to be, defamatory, libelous, hateful, racially or religiously biased, offensive, abusive, threatening or harassing to any person or entity;
  6. contains any computer viruses, worms or other potentially damaging computer programs or files;
  7. is lewd, profane, obscene, or indecent, including any content that is violent or pornographic or that contains nudity or explicit violent or sexual material; or
  8. offers or disseminates any fraudulent goods, services, schemes or promotions, unsolicited mass mailing or spamming, or unauthorized advertising.

You hereby agree to indemnify and hold Shire Human Genetic Therapies (and its officers, directors, employees, agents, and collaborators), harmless from all claims, demands, and damages (whether direct, indirect, special, consequential or punitive), known and unknown, including reasonable attorneys' fees, arising out of a breach of these Terms and Conditions, your violation of any law or the rights of a third party, Shire Human Genetic Therapies’ use or publication of content submitted by you, or otherwise relating to your use of the website.



If any dispute arises between us regarding these Terms and Conditions or your use of this website, it shall be resolved through good faith negotiations between the parties. If such efforts prove unsuccessful, all such controversies, claims, or disputes shall be submitted to binding arbitration pursuant to the Federal Arbitration Act, 9 U.S.C., §1 et seq. Arbitration shall be conducted in accordance with the rules of the American Arbitration Association. The arbitration award shall be final and binding, and it may be confirmed and enforced in any court of competent jurisdiction. Each party shall pay for all attorney fees it incurred in connection with the arbitration and shall share equally in the costs of the arbitration. The venue for any arbitration shall be New Jersey. Your access and use of the website and its content are governed by and shall be construed in accordance with the laws of the State of New Jersey.

You may address any questions or comments regarding these Terms and Conditions to Shire Human Genetic Therapies Inc., 300 Shire Way, Lexington, MA 02421 (“Shire Human Genetic Therapies”).


Warning: Possible bone cancer (osteosarcoma).

  • During animal drug testing, NATPARA caused some rats to develop a bone cancer called osteosarcoma.

Important Safety Information

What is the most important information I should know about NATPARA?

Warning: Possible bone cancer (osteosarcoma).

  • During animal drug testing, NATPARA caused some rats to develop a bone cancer called osteosarcoma. It is not known if people who take NATPARA will have a higher chance of getting osteosarcoma. Tell your doctor right away if you have pain in any areas of your body that does not go away, or any new or unusual lumps or swelling under your skin that is tender to touch.
  • NATPARA is only available through the NATPARA Risk Evaluation and Mitigation Strategy (REMS) Program. The purpose of the NATPARA REMS program is to inform patients about the potential risk of osteosarcoma associated with the use of NATPARA. For more information about this REMS program, call 1-855-NATPARA (628-7272) or go to www.NATPARAREMS.com.

NATPARA may cause other serious side effects, including:

High blood calcium (hypercalcemia)

  • NATPARA can cause some people to have a higher blood calcium level than normal.
    • Your doctor should check your blood calcium before you start and during your treatment with NATPARA.
    • Tell your doctor if you have nausea, vomiting, constipation, low energy, or muscle weakness. These may be signs that you have too much calcium in your blood.

Low blood calcium (hypocalcemia)

  • People who stop using or miss a dose of NATPARA may have an increased risk of severe low blood calcium levels.
  • Tell your doctor if you have tingling of your lips, tongue, fingers and feet, twitching of face muscles, cramping of feet and hands, seizures, depression, or have problems thinking or remembering.

Tell your doctor right away if you have any of these signs and symptoms of high or low blood calcium levels.

Who should not use NATPARA?

  • Do not use NATPARA if you are allergic to parathyroid hormone or any of the ingredients in NATPARA.

What should I tell my healthcare provider before using NATPARA?

  • Before you start using NATPARA, tell your doctor about all of your medical conditions. Tell your doctor about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

What are the possible side effects of NATPARA?

  • NATPARA may cause serious side effects like allergic (hypersensitivity) reaction, including anaphylaxis. Tell your healthcare provider or get emergency medical help right away if you have any of the following symptoms of an allergic reaction:
    • swelling of your face, lips, mouth, or tongue
    • breathing problems
    • fainting, dizziness, feeling lightheaded (low blood pressure)
    • fast heartbeat
    • itching
    • rash
    • hives
  • The most common side effects of NATPARA include: tingling, tickling, or burning feeling of the skin, low or high blood calcium, headache, nausea, reduced sense of touch or sensation, diarrhea, vomiting, pain in joints, too much calcium in urine, and pain in limbs.

These are not all the possible side effects of NATPARA. For more information, talk with your doctor.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see Prescribing Information, Medication Guide, and Instructions for Use.